Dr. Yueh-Ren Ho

Dr. Yueh-Ren Ho.

Tel: 5547 (Office) 5527 (Lab.)
E-mail: yrho@mail.ncku.edu.tw

Ph.D., National Cheng Kung University, R.O.C.

Biochemical metabolism
Medical education
Critical thinking
Clinical reasoning

Research Interest
My research is centered on constructing a host-vector system and developing an ARS (Autonomous replicating sequence) element containing secretion vector in eukaryotes. In order to investigate this system, some short and functional ARS elements are isolated from eukaroytic genomes, and an auxotrophic mutant strain is selected by EMS (Ethylmethane sulfonate) treatment . The constructed ARS-containing genomic libraries are transformed into the mutant strain to complete a functional host-vector system. At present, I am more interested in the mechanisms of tumor metastasis and microbial infection. Experiments in these area are in progress the mechanisms of tumor metastasis and microbial infection.


  1. Yueh-Ren Ho, Bao-Yu Chen, Chien-Ming Li. (2023). Thinking more wisely: using the Socratic method to develop critical thinking skills amongst healthcare students. BMC Medical Education, 23:173.

  2. CM Li, YR Ho, WL Chen, CH Lin, MY Chen, and YZ Chen. (2019). Nasogastric Tube Dislodgment Detection in Rehabilitation Patients Based on Fog Computing with Warning Sensors and Fuzzy Petri Net. Sensors and Materials, 31(1):117–130.

  3. 台灣醫學教育學會邀請發表電子報文章:基礎老師開臨床推理選修課?從學習觀點出發2019.03.15

  4. Wu JX, Li CM, Chen GC, Ho YR, Lin CH. (2017). Peripheral arterial disease screening for hemodialysis patients using a fractional-order integrator and transition probability decision-making model. IET Syst Biol., 11:69-76.

  5. Jian-Xing Wu, Chien-Ming Li, Yueh-Ren Ho, Ming-Jui Wu, Ping-Tzan Huang, and *Chia-Hung Lin. (2016). Bilateral Photoplethysmography Analysis for Peripheral Arterial Stenosis Screening with a Fractional-order Integrator and Info-Gap Decision-Making. IEEE Sensors Journal, 16:2691-2700.

  6. CM Li, YC Du, JX Wu, CH Lin, YR Ho, YJ Lin and TS Chen (2014, Jan). Synchronizing chaotification with support vector machine and wolf pack search algorithm for estimation of peripheral vascular occlusion in diabetes mellitus. Biomedical Signal Processing and Control , 9:45-55.

  7. CM Li, YC Du, JX Wu, CH Lin, YR Ho and TS Chen (2013, Jul). Dynamic analysis with a fractional-order chaotic system for estimation of peripheral arterial disease in diabetic foot. Meas Sci Technol , 24: 085701.

  8. Ho YR, Li CM, Yu CH, Lin YJ, Wu CM, Harn IC, Tang MJ, Chen YT, Shen FC, Lu CY, Tsai TC, Wu JJ. (2013). The enhancement of biofilm formation in Group B streptococcal isolates at vaginal pH. Med Microbiol Immunol. Med Microbiol Immunol , 202:105-115.

  9. CN Chuan, PX Zheng, YR Ho, HM Wu, WJ Chuang, YS Lin, MT Lin, CC Liu, and JJ Wu. (2009). emm1/Sequence Type 28 Strains of Group A Streptococci That Express covR at Early Stationary Phase Are Associated with Increased Growth and Earlier SpeB Secretion. J Clin Microbiol 47:3161-3169

  10. E. van Elzakker, R. Yahiaoui, C. Visser, P. Oostvogel, A Muller, YR Ho, JJ Wu, A. van Belkum. (2009). Epidemiology of and prenatal molecular distinction between invasive and colonizing group B streptococci in The Netherlands and Taiwan. Eur J Clin Microbiol Infect Dis. 28:921-928

  11. RP Janapatla, YR Ho, JJ Yan, HM Wu, JJ Wu. (2008). The Prevalence of Erythromycin Resistance in Group B Streptococcal Isolates at a University Hospital in Taiwan. Microbial Drug Resistance. 14:293-297

  12. HM Wu, RP Janapatla, YR Ho, KH Hung, CW Wu, JJ Yan, and JJ Wu. (2008). Emergence of fluoroquinolone resistance in Group B streptococcal isolates in Taiwan. Antimicrobial Agent and Chemotherapy:52:1888-1890

  13. YR Ho, CM Li, HP Su, JH Wu, YC Tseng, YJ Lin, JJ Wu. (2007). Variation in the number of tandem repeats and profile of surface protein genes among invasive group B streptococci correlates with patient age. J Clin Microbiol. 45:1634-1636

  14. CM Li, Y-Y Lee, YR Ho. (2002). Acute meningoencephalitis as initial presentation of human immunodeficiency virus infection: report of 2 cases and literature review. J Microbiol immunol Infect. 35:195-198

  15. CM Li, KH Chiang, YH Chen, and YR Ho. (2002). Case-holding investigation of a cohort with newly-diagnosed tuberculosis. J gen mol biol. 13:155-159

  16. CM Li, YR Ho. (2001). Cotraindication of shiomarin in patients with cirrhosis and malignancy of liver. Lett of Assoc Taiwan Int Med. 116:6-7

  17. CM Li, PO Chen, and YR Ho. (2001). Non-clostridal gas gangrene caused by Klebsiella pneumoniae: a case report. Scand J Infect Dis. 33: 629-630

  18. CM Li, YR Ho, YC Liu. (2001). Transmission of human immunodeficiency virus through bone transplantation: a case report. J Formos Med Assoc. 100: 350-351

  19. Wu JD, Hsueh HC, Huang WT, Liu HS, Leung HW, Ho YR, Lin MT, Lai MD. (1997). The inducible lactose operator-repressor system is functional in the whole animal. DNA Cell Biol.16:17-22

  20. Lee JC, Lee TS, Ho HY, Hsueh HC, Huang WT, Ho YR, Lai MD. (1996). Expression pattern of nuclear p53 is unique in COS-1 cells. Anticancer Res.16:2705-8

  21. Ho YR, Chang MC. (1988). Cloning of a LEU gene and an ARS site of Rhodotorula glutinis. Zhonghua Min Guo Wei Sheng Wu Ji Mian Yi Xue Za Zhi. 21:1-8

Seminar paper
  1. 何月仁、陳寶玉、陳思蘋、李健明 (2022) 醫者議也—臨床推理技能之同儕學習. 111醫學教育學會年會 Poster 111-094

  2. YH Chang, YR Ho, CM Li (2022) Shigella flexneri and cytomegalovirus colitis in an AIDS patient: case report and literature review. The 9th Annual Meeting of the Taiwan AIDS Society, Taipei, Poster 111-P15

  3. 何月仁、蔡晴、陳寶玉、李健明 (2021) 以技能本位課程提升醫學生批判性思考於臨床學習之探討. 台灣醫學教育學會年會Poster 110-062

  4. 何月仁、陳寶玉、李健明(2020) 醫學生批判思考技能之學習歷程:以生化實驗課程為例. 台灣醫學教育學會年會poster 109-069

  5. 何月仁、陳寶玉、李健明 (2019) 醫學四年級初階臨床推理技能之學習評估: SCT-GM檢測的應用. 台灣醫學教育學會年會poster 108-62

  6. 何月仁、陳寶玉、李健明 (2019) 案例報告工作坊:「臨床推理」技能之同儕學習. 教學實踐研究研討會 poster GC-04

  7. Chien-Ming Li、Yueh-Ren Ho (2018). Melioidosis masquerading as chronic ulcer plus pneumonia and bacteremic frontal osteomyelitis: case report and literature review. Annual Meeting of Taiwan Society of Internal Medicine, Medical College of National Taiwan University, Taipei. Poster 107-76(corresponding author).
  8. Chien-Ming Li、Yueh-Ren Ho (2018). Cat-bite associated right hand abscess and metacarpal osteomyelitis one week after the accident: case report and literature review. Annual Meeting of Taiwan Society of Internal Medicine, Medical College of National Taiwan University, Taipei.Poster 107-77(corresponding author)
  9. Ming-Yu Chen、Yun-Tzu Chen、Yueh-Ren Ho、Chien-Ming Li、Wei-Ling Chen、Jar-Hong Lin. (2018, Jun). Combination of fog computing and warning sensor with fuzzy Petri net (FPN) to detect dislodgement of nasogastric tube in rehabilitation department. 2018 Intelligent Living Technology Conference, National Chin-Yi University of Technology, Taichung city.

  10. 陳銘宇, 陳泳志, 何月仁, 李健明, 陳維聆, 林家宏 (2018, Jun). 基於霧端計算結合警示感測器與模糊派萃網路(FPN)於復健病人鼻胃管(NG)自拔與脫落偵測輔具之研製. 2017第十三屆智慧生活科技研討會(嵌入式系統開發與應用), 國立勤益科技大學.

  11. YR Ho, WJ Chuang, CM Li. (2017, Oct). Potential Impact of Biochemistry Laboratory Worksheet on Learning of Critical Thinking Skills of n Students in a Medical College. Annual Meeting of Taiwan Association of Medical Education, China Medical University. Poster106-053

  12. Ping-Tzan Huang, Chih-Cheng Kao, Chien-Ming Li, Yueh-Ren Ho, Wei-Ling Chen, and Chia-Hung Lin (2016, Sep). The Feasibility of Integrating Flexible Sensor and Virtual Self-Organizing DC Grid Model in an Embedded System for Blood Leakage Detection During Dialysis Treatment. The 4th IIAE International Conference on Intelligent Systems and Image Processing, Kyoto, Japan.

  13. Eddie Y. Z. Shi, Yueh-Ren Ho, Chien-Ming Li (2016, Jan). Pel-Ebstein fever pattern in a 73-year-old man of primary hepatic Hodgkin lymphoma presenting with fever of unknown origin. Annual meeting of The Infectious Disease Society of Taiwan, Medical College of National Taiwan University, Taipei. Poster105-053

  14. Ming-Jui Wu, Yueh-Ren Ho, Chien-Ming Li, Yi-Chun Du, and Chia-Hung Lin (2014, Dec). Screening for Arteriovenous Fistula Dysfunction with Bilateral Photoplethysmography and Game Theory. Hong Kong International Conference on Engineering and Applied Science, Hong Kong