成大醫學院婦產科
郭保麟 教授

Professor Pao-Lin Kuo

通訊地址： 70428 台南市勝利路138號 成大醫院婦產部
連絡電話： (06)2353535#5263
E-mail： paolink@mail.ncku.edu.tw

學歷
台大醫學院 醫學士 (1984)

經歷
2003-迄今 成大醫學院 教授
2004-2010 成大醫院婦產部 主任
2003-2005 成大醫院遺傳中心 主任
1993-1995 National Genome Center, National Institute of Health Exchange Scientist
1986-1989 臺大醫院婦產科 住院醫師，總住院醫師
1984-1986 長庚醫院婦產科 住院醫師

榮譽及獲獎
1997 杜聰明博士優秀論文獎 (Formosan Medical Association)
1998 日本婦產科醫學會優秀論文獎
2002 日本婦產科醫學會優秀論文獎

專長領域
● Human genetics disease and prenatal diagnosis
● Human reproductive failures

Publications:

  1. Tsai YC, Tseng JT, Wang CY, Su MZ, Huang JY, Kuo PL (corresponding author). Medroxyprogesterone acetate drives M2 macrophage differentiation toward a phenotype of decidual macrophage. Molecular and Cellular Endocrinology doi: 10.1016/j.mce.2017.05.015 SCI

  2. Shen YR, Wang HY, Kuo YC, Shih SC, Hsu CH, Chen YR, Wu SR, Wang CY, Kuo PL (corresponding author). SEPT12 phosphorylation results in loss of the septin ring/sperm annulus， defective sperm motility and poor male fertility. PLOS Genetics 20171(3): e1006631 doi: 10.1371/journal.pgen.1006631 SCI

  3. Kuo YC, Shen YR, Chen HI, Lin YH, Wang YY, Chen YR, Wang CY, Kuo PL (corresponding author). SEPT12 orchestrates the formation of mammalian sperm annulus by organizing SEPT12-7-6-2/-4 core complexes. Journal of Cell Science 2015;128(5):923-934 SCI

  4. Kuo PL, Hung YL, Hsieh CCJ, Lin BW, Lee JC, Hung LY. STK31 is a cell-cycle regulated protein that contributes to the tumorigenecity of epithelial cancer cells. PLoS One 2014;9(3);e93303 SCI

  5. Huang JY, Su MT, Lin SH, Kuo PL (corresponding author). A genetic study of NLRP2 and NLRP7 genes in idiopathic recurrent miscarriage. Human Reproduction 2013;28:127-134 SCI

  6. Su MT, Lin SH, Chen YC, Kuo PL (corresponding author). Genetic association of ACE and PAI-1 genes in women with recurrent pregnancy loss A Systemic Review and Meta-Analysis. Thrombosis and Haemostasis 2013;109:8-15 SCI

  7. Teng YN, Chang YP, Tseng JT, Kuo PH, Lee IW, Lee MS, Kuo PL (corresponding author). A Single nucleotide polymorphism of DAZL gene promoter confer susceptibility to spermatogenic failure in the Taiwanese Han. Human Reproduction 2012;27:2857-2865 SCI

  8. Lin YH, Wang YY, Chen HI, Kuo YC, Chiou YW, Lin HH, Wu CM, Hsu CC, Chiang HS, Kuo PL (corresponding author). SETPTIN12 genetic variants confer susceptibility to teratozoospermia. PLoS One 2012;7(3):e34011 SCI

  9. Kuo YC, Lin YH, Chen HI, Wang YY, Chiou YW, Lin HH, Pan HA, Wu CM, Su SM, Hsu CC, Kuo PL (corresponding author). SEPT12 mutations cause male infertility with defective sperm annulus. Human Mutation 2012;33(4):710-719 SCI

  10. Wu CH, Guo CY, Yang JG, Tsai HD, Chang YJ, Tsai PC, Hsu CC, Kuo PL (corresponding author). Polymorphisms of dioxin receptor complex components and detoxification-related genes jointly confer susceptibility to advanced stage endometriosis in the Taiwanese Han population. American Journal of Reproductive Immunology 2012;67(2)160-168 SCI