Ming-Shi Chang

Chair Professor

Prof. Ming-Shi Chang

Prof. Ming-Shi Chang's own Home Page

Publications:

  1. Huang TH, Lewis JL, Lin HS, Kuo LT, Mao SW, Tai YS, Chang MS, Ables GP, Perrone CE, Yang RS. A methionine-restricted diet and endurance exercise decrease bone mass and extrinsic strength but increase intrinsic strength in growing male rats. J Nutr. 2014 [Abstract]

  2. Hsu YH, Chang MS. The therapeutic potential of anti-interleukin-20 monoclonal antibody. Cell Transplant. 2014 [Abstract]

  3. Hsu YH, Li HH, Sung JM, Chen WT, Hou YC, Chang MS. Interleukin-19 mediates tissue damage in murine ischemic acute kidney injury. PLoS One. 2013 [Abstract]

  4. Hsu YH, Wei CC, Shieh DB, Chan CH, Chang MS. Anti-IL-20 monoclonal antibody alleviates inflammation in oral cancer and suppresses tumor growth. Mol Cancer Res. 2012 [Abstract]

  5. Hsu YH, Hsieh PP, Chang MS. Interleukin-19 blockade attenuates collagen-induced arthritis in rats. Rheumatology (Oxford). 2012 [Abstract]

  6. Hsu YH, Hsing CH, Li CF, Chan CH, Chang MC, Yan JJ, Chang MS. Anti-IL-20 monoclonal antibody suppresses breast cancer progression and bone osteolysis in murine models. J Immunol. 2012 [Abstract]

  7. Hsu YH, Chen WY, Chan CH, Wu CH, Sun ZJ, Chang MS. Anti-IL-20 monoclonal antibody inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss. J Exp Med. 2011 [Abstract]

  8. Hsu YH, Chang MS. Interleukin-20 antibody is a potential therapeutic agent for experimental arthritis. Arthritis Rheum. 2010 [Abstract]

  9. Chen WY, Chang MS. IL-20 is regulated by hypoxia-inducible factor and up-regulated after experimental ischemic stroke. J Immunol. 2009 [Abstract]

  10. Wei CC, Chang MS. Mouse interleukin-20 receptor 1a targets renal epithelial cells and is associated with renal calcium deposition. Genes Immun. 2009 [Abstract]

  11. Wei CC, Chang MS. A novel transcript of mouse interleukin-20 receptor acts on glomerular mesangial cells as an aggravating factor in lupus nephritis. Genes Immun. 2008 [Abstract]

  12. Li HH, Cheng HH, Sun KH, Wei CC, Li CF, Chen WC, Wu WM, Chang MS. Interleukin-20 targets renal mesangial cells and is associated with lupus nephritis. Clin Immunol. 2008 [Abstract]

  13. Wei CC, Li HH, Hsu YH, Hsing CH, Sung JM, Chang MS. Interleukin-20 targets renal cells and is associated with chronic kidney disease. Biochem Biophys Res Commun. 2008 [Abstract]

  14. Huang KY, Lin RM, Chen WY, Lee CL, Yan JJ, Chang MS. IL-20 may contribute to the pathogenesis of human intervertebral disc herniation. Spine (Phila Pa 1976). 2008 [Abstract]

  15. Li HH, Hsu YH, Wei CC, Lee PT, Chen WC, Chang MS. Interleukin-20 induced cell death in renal epithelial cells and was associated with acute renal failure. Genes Immun. 2008 [Abstract]

  16. Hsing CH, Chiu CJ, Chang LY, Hsu CC, Chang MS. IL-19 is involved in the pathogenesis of endotoxic shock. Shock. 2008 [Abstract]

  17. Hsing CH, Hsu CC, Chen WY, Chang LY, Hwang JC, Chang MS. Expression of IL-19 correlates with Th2 cytokines in uraemic patients. Nephrol Dial Transplant. 2007 [Abstract]

  18. Huang KY, Yan JJ, Hsieh CC, Chang MS, Lin RM. The in vivo biological effects of intradiscal recombinant human bone morphogenetic protein-2 on the injured intervertebral disc: an animal experiment. Spine (Phila Pa 1976). 2007 [Abstract]

  19. Chen WY, Cheng BC, Jiang MJ, Hsieh MY, Chang MS. IL-20 is expressed in atherosclerosis plaques and promotes atherosclerosis in apolipoprotein E-deficient mice. Arterioscler Thromb Vasc Biol. 2006 [Abstract]

  20. Hsu YH, Li HH, Hsieh MY, Liu MF, Huang KY, Chin LS, Chen PC, Cheng HH, Chang MS. Function of interleukin-20 as a proinflammatory molecule in rheumatoid and experimental arthritis. Arthritis Rheum. 2006 [Abstract]

  21. Wei CC, Hsu YH, Li HH, Wang YC, Hsieh MY, Chen WY, Hsing CH, Chang MS. IL-20: biological functions and clinical implications. J Biomed Sci. 2006 [Abstract]

  22. Hsing CH, Ho CL, Chang LY, Lee YL, Chuang SS, Chang MS. Tissue microarray analysis of interleukin-20 expression. Cytokine. 2006 [Abstract]

  23. Wei CC, Chen WY, Wang YC, Chen PJ, Lee JY, Wong TW, Chen WC, Wu JC, Chen GY, Chang MS, Lin YC. Detection of IL-20 and its receptors on psoriatic skin. Clin Immunol. 2005 [Abstract]

  24. Li HH, Lin YC, Chen PJ, Hsiao CH, Lee JY, Chen WC, Tzung TY, Wu JC, Chang MS. Interleukin-19 upregulates keratinocyte growth factor and is associated with psoriasis. Br J Dermatol. 2005 [Abstract]

  25. Chen WY, Cheng YT, Lei HY, Chang CP, Wang CW, Chang MS. IL-24 inhibits the growth of hepatoma cells in vivo. Genes Immun. 2005 [Abstract]

  26. Liao SC, Cheng YC, Wang YC, Wang CW, Yang SM, Yu CK, Shieh CC, Cheng KC, Lee MF, Chiang SR, Shieh JM, Chang MS. IL-19 induced Th2 cytokines and was up-regulated in asthma patients. J Immunol. 2004 [Abstract]

  27. Wei CC, Ho TW, Liang WG, Chen GY, Chang MS. Cloning and characterization of mouse IL-22 binding protein. Genes Immun. 2003 [Abstract]

  28. Liao YC, Liang WG, Chen FW, Hsu JH, Yang JJ, Chang MS. IL-19 induces production of IL-6 and TNF-alpha and results in cell apoptosis through TNF-alpha. J Immunol. 2002 [Abstract]

  29. Senaldi G, Varnum BC, Sarmiento U, Starnes C, Lile J, Scully S, Guo J, Elliott G, McNinch J, Shaklee CL, Freeman D, Manu F, Simonet WS, Boone T, Chang MS. Novel neurotrophin-1/B cell-stimulating factor-3: a cytokine of the IL-6 family. Proc Natl Acad Sci U S A. 1999 [Abstract]

  30. Andrew DP, Chang MS, McNinch J, Wathen ST, Rihanek M, Tseng J, Spellberg JP, Elias CG 3rd. STCP-1 (MDC) CC chemokine acts specifically on chronically activated Th2 lymphocytes and is produced by monocytes on stimulation with Th2 cytokines IL-4 and IL-13. J Immunol. 1998 [Abstract]

  31. Chang MS, McNinch J, Elias C 3rd, Manthey CL, Grosshans D, Meng T, Boone T, Andrew DP. Molecular cloning and functional characterization of a novel CC chemokine, stimulated T cell chemotactic protein (STCP-1) that specifically acts on activated T lymphocytes. J Biol Chem. 1997 [Abstract]

  32. Simonet WS, Lacey DL, Dunstan CR, Kelley M, Chang MS, Lüthy R, Nguyen HQ, Wooden S, Bennett L, Boone T, Shimamoto G, DeRose M, Elliott R, Colombero A, Tan HL, Trail G, Sullivan J, Davy E, Bucay N, Renshaw-Gegg L, Hughes TM, Hill D, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density. Cell. 1997 [Abstract]

  33. Chang MS, Hsu RY, McNinch J, Copeland NG, Jenkins NA. The gene for murine megakaryocyte growth and development factor (thrombopoietin, Thpo) is located on mouse chromosome 16. Genomics. 1995 [Abstract]

  34. Chang MS, McNinch J, Basu R, Shutter J, Hsu RY, Perkins C, Mar V, Suggs S, Welcher A, Li L, et al. Cloning and characterization of the human megakaryocyte growth and development factor (MGDF) gene. J Biol Chem. 1995 [Abstract]

  35. Chang MS, McNinch J, Basu R, Simonet S. Cloning and characterization of the human neutrophil-activating peptide (ENA-78) gene. J Biol Chem. 1994 [Abstract]

  36. Chang MS, Engel G, Benedict C, Basu R, McNinch J. Isolation and characterization of the human interleukin-9 receptor gene. Blood. 1994 [Abstract]

PATENTS

  1. Ming-shi Chang
    Antibody to IL-20 and method for inhibiting IL-20 Induced cell proliferation
    US patent7435800

  2. Ming-shi Chang
    Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseases
    US Patent Number 7611705B2

  3. Ming-shi Chang
    Anti-IL-20 antibody and its use in treating IL-20 associated inflammatory diseases
    US Patent Number 7,786,274.

  4. Ming-shi Chang
    Anti-IL-20 antibody and its use in treating IL-20 associated osteoporosis
    US Patent Number 7,837,994

  5. Ming-shi Chang
    Anti-IL-20 antibody and its use in treating stroke
    US Patent 8,012,478

  6. Ming-shi Chang, David G. Lowe and David G. Goeddel.
    Composition and Methods for Synthesis of Natriuretic Protein Receptor B and Method of Use.
    U.S. Patent Number 5352587

  7. Ming-shi Chang
    A novel neurotrophic protein (NNT-1)
    U.S. Patent Number 5741772

  8. Ming-shi Chang
    Antibodies to the neurotrophic factor NNT-1
    U.S. Patent Number 6143874

  9. Ming-shi Chang
    Nucleic acid molecules encoding the neurotrophic factor NNT-1
    U.S. Patent Number 6054294

  10. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    U.S. Patent Number 6015938

  11. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 6613544

  12. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 6369027

  13. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 6288032

  14. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 6284740

  15. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 6284728

  16. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 6284485

  17. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 7005413

  18. Ming-shi Chang, Bill Boyle, Frank Calzone and David Lacey
    Osteoprotegerin
    US Patent Number 7632922

  19. Ming-shi Chang and Christiaan Saris
    Nucleic acid molecules encoding thymic stromal lympopoietin receptor proteins and a process for producing the encoded polypeptides thereof
    US Patent Number 7964713

Return to NCKU Chinese Main Page of Biochem 回到生化所

Send comments or Suggestion to this email_box.

Updated: 2014.11.19