成大醫院外科部
徐慧萍 副教授

Dr. Hui-Ping Hsu

通訊地址： 70124 台南市北區勝利路138號 成大醫院外科部
連絡電話： (06)2353535 #5893(辦公室), 5272(實驗室)
E-mail： hphsu@mail.ncku.edu.tw

學歷
國立成功大學臨床醫學研究所 博士 (2011)
國立成功大學 醫學士 (1984)

經歷
2017-迄今 國立成功大學醫學系外科學科 副教授
2005-迄今 國立成功大學醫學院附設醫院外科 主治醫師
2016-2017 國立成功大學醫學系外科學科 臨床副教授
2011-2016 國立成功大學醫學系外科學科 臨床助理教授
2005-2007 國立成功大學醫學院附設醫院斗六分院外科 主治醫師
2004-2005 國立成功大學醫學院附設醫院外科 總住院醫師
2000-2005 國立成功大學醫學院附設醫院外科 住院醫師

專長領域
乳房外科、腫瘤外科、消化系外科、轉譯醫學、腫瘤免疫學

研究方向
研究方向著重於解決臨床治療病人之問題。過去主要在於消化道癌症 與外科腫瘤學，已建立壺腹周圍癌症在根除性手術後的臨床資料庫， 同時致力於壺腹癌病人轉移與復發的研究，研究主題包含腫瘤微環境 （cancer microenvironment）、細胞表面黏附因子、動物實驗模式、 癌症復發之預測因子等。近年來配合臨床分科之轉換，著重於乳癌病 人的照顧，研究方向也轉換至與乳癌相關的方向。

研究方向
目前台灣癌症發生率逐年上升，其中女性乳癌罹病上升率居冠。在臨床 治療病人時，面臨到多種問題；因此，目前本人致力於建立本院乳癌病 人的臨床資料庫，並積極研究乳癌的復發或抗藥性機轉，著重於乳癌細 胞與宿主免疫系統的交互作用，利用生物統計與生物資訊的分析技術， 期望藉此能開發出更新更好的治療方式，提升病人的存活。

Publications:

  1. Yen-Hung Wu, I-Jeng Yeh, Nam Nhut Phan, Meng-Chi Yen, Jui-Hsiang Hung, Chung-Chieh Chiao, Chien-Fu Chen, Zhengda Sun, Hui-Ping Hsu*, Chih-Yang Wang*, Ming-Derg Lai*. Gene signatures and potential therapeutic targets of Middle East respiratory syndrome coronavirus (MERS-CoV)-infected human lung adenocarcinoma epithelial cells. J Microbiol Immunol Infect 2021 Oct; 54(5): 845-857. (SCI, co-corresponding author) (出版地點: Taiwan, 5-Year Impact Factor: 3.376)

  2. Yi-Ling Chen, Chih-Yang Wang, Jung-Hua Fang, Hui-Ping Hsu*. Serine/threonine-protein kinase 24 is an inhibitor of gastric cancer metastasis through suppressing CDH1 gene and enhancing stemness. Am J Cancer Res. 2021 Sep 15;11(9):4277-4293. (SCI, corresponding author) (出版地點: USA, 5-Year Impact Factor: 5.863) (送審代表著作)

  3. Peng-Chan Lin, Yu-Min Yeh, Hui-Ping Hsu, Ren-Hao Chan, Bo-Wen Lin, Po-Chuan Chen, Chien-Chang Pan, Keng-Fu Hsu, Jenn-Ren Hsiao, Yan-Shen Shan, Meng-Ru Shen. Comprehensively exploring the mutational landscape and patterns of genomic evolution in hypermutated cancers. Cancers (Basel) 2021 Aug 26; 13(17): 4317. (SCI) (出版地點: Switzerland, 5-Year Impact Factor: 6.999)

  4. Zhu-Jun Loh, Kuo-Ting Lee, Ya-Ping Chen, Yao-Lung Kuo, Wei-Pang Chung, Ya-Ting Hsu, Chien-Chang Huang, Hui-Ping Hsu*. False-Negative frozen section of sentinel nodes in early breast cancer (cT1-2N0) patients. World J Surg Oncol 2021 Jun 22; 19(1): 183. (SCI, corresponding author) (出版地點: England, 5-Year Impact Factor: 2.777)

  5. Li-Chin Cheng, Tzu-Jen Kao, Nam Nhut Phan, Chung-Chieh Chiao, Meng-Chi Yen, Chien-Fu Chen, Jui-Hsiang Hung, Jia-Zhen Jiang, Zhengda Sun, Chih-Yang Wang*, Hui-Ping Hsu*. Novel signaling pathways regulate SARS-CoV and SARS-CoV-2 infectious disease. Medicine (Baltimore) 2021 Feb 19; 100(7): e24321. (SCI, co-corresponding author) (出版地點: USA, 5-Year Impact Factor: 2.351)

  6. Pin-Shern Chen†, Hui-Ping Hsu†, Nam Nhut Phan, Meng-Chi Yen, Feng-Wei Chen, Yu-Wei Liu, Fang-Ping Lin, Sheng-Yao Feng, Tsung-Lin Cheng, Pei-Hsiang Yeh, Hany A Omar, Zhengda Sun, Jia-Zhen Jiang, Yi-Shin Chan, Ming-Derg Lai, Chih-Yang Wang*, Jui-Hsiang Hung*. CCDC167 as a potential therapeutic target and regulator of cell cycle-related networks in breast cancer. Aging-US 2021 Jan 10; 13(3): 4157-4181. (SCI, co-first authors) (出版地點: USA, 5-Year Impact Factor: 6.380) (送審參考著作)

  7. Wei-Pang Chung, Kuo-Ting Lee, Ya-Ping Chen, Ya-Ting Hsu, Zhu-Jun Loh, Chien-Chang Huang, Hui-Ping Hsu*. The prognosis of early-stage breast cancer in extremely young female patients in a single institute. Medicine (Baltimore) 2021 Jan 8; 100(1): e24076. (SCI, corresponding author) (出版地點: USA, 5-Year Impact Factor: 2.351)

  8. Yen-Hung Wu, I-Jeng Yeh, Nam Nhut Phan, Meng-Chi Yen, Hsin-Liang Liu, Chih-Yang Wang*, Hui-Ping Hsu*. Severe acute respiratory syndrome coronavirus (SARS-CoV)-2 infection induces dysregulation of immunity: in silico gene expression analysis. Int J Med Sci 2021 Jan 1;18(5):1143-1152. (SCI, co-corresponding author) (出版地點: Australia, 5-Year Impact Factor: 3.508)

  9. Chih-Yang Wang, Ying-Jui Chao, Yi-Ling Chen, Tzu-Wen Wang, Nam Nhut Phan, Hui-Ping Hsu*, Yan-Shen Shan, Ming-Derg Lai. Upregulation of peroxisome proliferator-activated receptor-α and the lipid metabolism pathway promotes carcinogenesis of ampullary cancer. Int J Med Sci 2021 Jan 1; 18(1): 256-269. (SCI, corresponding author) (出版地點: Australia, 5-Year Impact Factor: 3.508)

  10. Hsin-Liang Liu, I-Jeng Yeh, Nam Nhut Phan, Yen-Hung Wu, Meng-Chi Yen, Jui-Hsiang Hung, Chung-Chieh Chiao, Chien-Fu Chen, Zhengda Sun, Jia-Zhen Jiang, Hui-Ping Hsu*, Chih-Yang Wang*, Ming-Derg Lai*. Gene signatures of SARS-CoV/SARS-CoV-2-infected ferret lungs in short- and long-term models. Infect Genet Evol 2020 Nov; 85: 104438. (SCI, co-corresponding authors) (出版地點: Netherlands, 5-Year Impact Factor: 3.188)

  11. Li-Chin Cheng, Ying-Jui Chao, Michael J., Overman, Chih-Yang Wang, Nam Nhut Phan, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Yan-Shen Shan*, Ming-Derg Lai. Increased expression of secreted frizzled related protein 1 (SFRP1) predicts ampullary adenocarcinoma recurrence. Sci Rep 2020 Aug 6; 10: 13255. (SCI, co-corresponding authors) (出版地點: England, 5-Year Impact Factor: 5.134) (送審參考著作)

  12. Li-Chin Cheng, Ying-Jui Chao, Chih-Yang Wang, Nam Nhut Phan, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu*, Yih-Jyh Lin, Yan-Shen Shan*, Ming-Derg Lai. Cancer-derived transforming growth factor-b modulates tumor-associated macrophages in ampullary cancer. OncoTargets Ther 2020 Aug 3; 13: 7503-7516. (SCI, co-corresponding authors) (出版地點: England, 5-Year Impact Factor: 3.763)

  13. Yi-Yi Lin, Chih-Yang Wang, Nam Nhut Phan, Chung-Chieh Chiao, Chung-Yen Li, Zhengda Sun, Jui-Hsiang Hung, Yi-Ling Chen, Meng-Chi Yen, Tzu-Yang Weng, Hui-Ping Hsu*, Ming-Derg Lai*. PODXL2 maintains cellular stemness and promotes breast cancer development through the Rac1/Akt pathway. Int J Med Sci 2020 Jun 29; 17(11): 1639-1651. (SCI, co-corresponding authors) (出版地點: Australia, 5-Year Impact Factor: 3.508)

  14. Nam Nhut Phan, Shirui Liu, Chih-Yang Wang, Hui-Ping Hsu, Ming-Derg Lai, Chung-Yen Li, Chien-Fu Chen, Chung-Chieh Chiao, Meng-Chi Yen, Zhengda Sun, Jia-Zhen Jiang*. Overexpressed gene signature of EPH receptor A/B family in cancer patients-comprehensive analyses from the public high-throughput database. Int J Clin Exp Pathol 2020 May 1; 13(5): 1220-1242. (SCI, co-first authors) (出版地點: USA, 5-Year Impact Factor: 0.01351)

  15. Chih-Yang Wang, Chung-Chieh Chiao, Nam Nhut Phan, Chung-Yen Li, Zheng-Da Sun, Jia-Zhen Jiang, Jui-Hsiang Hung, Yi-Ling Chen, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Hui-Ping Hsu*, Ming-Derg Lai*. Gene signatures and potential therapeutic targets of amino acid metabolism in estrogen receptor-positive breast cancer. Am J Cancer Res 2020 Jan 1; 10(1): 95-113. (SCI, co-corresponding authors) (出版地點: USA, 5-Year Impact Factor: 5.863) (送審代表著作)

  16. Hui-Ping Hsu, Chih-Yang Wang, Pei-Yin Hsieh, Jung-Hua Fang, Yi-Ling Chen*. Knockdown of serine/threonine-protein kinase 24 promotes tumorigenesis and myeloid-derived suppressor cell expansion in an orthotopic immunocompetent gastric cancer animal model. J Cancer 2020 Jan 1; 11(1): 213-228. (SCI, first author) (出版地點: Australia, 5-Year Impact Factor: 4.277)

  17. Chih-Yang Wang, Yung-Chieh Chang, Yao-Lung Kuo, Kuo-Ting Lee, Pai-Sheng Chen, Chun Hei Antonio Cheung, Chih-Peng Chang, Nam Nhut Phan, Meng-Ru Shen, Hui-Ping Hsu*. Mutation of the PTCH1 gene predicts recurrence of breast cancer. Sci Rep 2019 Nov 8; 9: 16359.1-1639.14. (SCI, corresponding author) (出版地點: England, 5-Year Impact Factor: 5.134) (送審參考著作)

  18. Chia-Yi Su, Ruei-Liang Yan, Wen-Hsin Hsu, Ching-Tung Chu, Hsuan-Chia Chang, Chien-Chen Lai, Hui-Ping Hsu, Hong-Chen Chen*. Phosphorylation of adducin-1 by cyclin-dependent kinase 5 is important for epidermal growth factor-induced cell migration. Sci Rep 2019 Sep 23; 9(1): 13703.e1-13703.e11. (SCI) (出版地點: England, 5-Year Impact Factor: 5.134)

  19. Wei-Pang Chung, Ya-Tin Hsu, Ya-Ping Chen, Hui-Ping Hsu*. Treatment of a patient with breast cancer and glucose 6-phosphate dehydrogenase deficiency: a case report. Medicine (Baltimore) 2019 Mar; 98(13): e14987.1-e14987.3. (SCI, corresponding author) (出版地點: USA, 5-Year Impact Factor: 2.351)

  20. Tsung-Han Yang, Jen-Lung Chen, Yih-Jyh Lin, Ying-Jui Chao, Yan-Shen Shan, Hui-Ping Hsu, Zhe-Min Su, Chung-Ching Chou, Yi-Ting Yen*. Laparoscopic surgery for large left lateral liver tumors: safety and oncologic outcomes. Surg Endosc 2018 Oct; 32(10): 4314-4320. (SCI) (出版地點: USA, 5-Year Impact Factor: 4.595)

  21. Tzu-Yang Weng, Hsuan Franziska Wu, Chung-Yen Li, Yu-Hsuan Hung, Yu-Wei Chang, Yi-Ling Chen, Hui-Ping Hsu, Yu-Hung Chen, Chih-Yang Wang, Jang-Yang Chang, Ming-Derg Lai*. Homoharringtonine induced immune alteration for an efficient anti-tumor response in mouse models of non-small cell lung adenocarcinoma expressing Kras Mutation. Sci Rep 2018 May 29; 8(1): 8216. (SCI) (出版地點: England, 5-Year Impact Factor: 5.134)

  22. Tzu-Yang Weng, Chia-Jung Li, Chung-Yen Li, Yu-Hsuan Hung, Meng-Chi Yen, Yu-Wei Chang, Yu-Hung Chen, Yi-Ling Chen, Hui-Ping Hsu, Jang-Yang Chang, Ming-Derg Lai*. Skin delivery of Clec4a small hairpin RNA elicited an effective antitumor response by enhancing CD8+ immunity in vivo. Mol Ther Nucleic Acids. 2017 Dec 15; 9: 419-427. (SCI) (出版地點: USA, 5-Year Impact Factor: 8.334)

  23. Chih-Yang Wang, Chung-Yen Li, Hui-Ping Hsu, Chien-Yu Cho, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Yu-Hsuan Hung, Kuo-Ting Lee, Jui-Hsiang Hung, Yi-Ling Chen, Ming-Derg Lai*. PSMB5 plays a dual role in cancer development and immunosuppression. Am J Cancer Res 2017 Nov 1; 7(11): 2103-2120. (SCI) (出版地點: USA, 5-Year Impact Factor: 5.863)

  24. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Yu-Hsuan Hung, Chih-Yang Wang, Meng-Chi Yen and Yi-Ling Chen. Cyclin D1 overexpression correlates with poor tumor differentiation and prognosis in gastric cancer. Oncol Lett. 2017 Oct; 14(4): 4517-4526. doi: 10.3892/ol.2017.6736 (SCI) 本人為共同第一作者

  25. Hui-Ping Hsu, Ming-Derg Lai, Jenq-Chang Lee, Meng-Chi Yen, Tzu-Yang Weng, Wei-Ching Chen, Jung-Hua Fang, Yi-Ling Chen. Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling. Sci Rep. 2017 Jul 19; 7(1): 5823.e1-5823.e14. doi: 10.1038/s41598-017- 04952-7 (SCI)

  26. Zhu-Jun Loh, Kuo-Ting Lee, Wei-Pang Chung, Wen-Chung Chen, Hsueh-Li Kuo, Po-Jun Chen, Hsi-Huei Lu, Hui-Ping Hsu. Invasive lobular carcinoma of the breast with synchronous colon metastasis. Formosan J Surg. 2017 Apr; 50(2): 69-73 (國內期刊：外科醫學會雜誌)

  27. Hau-Lun Huang, Wei-Ching Chen, Hui-Ping Hsu, Chien-Yu Cho, Yu-Hsuan Hung, Chih-Yang Wang, Ming-Derg Lai. Silencing of argininosuccinate lyase inhibits colorectal cancer formation. Oncol Rep. 2017 Jan; 37(1): 163-170. doi: 10.3892/or.2016.5221 (SCI)

  28. Wei-Ching Chen, Hui-Ping Hsu, Yu-Hsuan Hung, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, and Ming-Derg Lai. Cancer stem cell marker CD90 inhibits the ovarian cancer formation via β3 integrin. Int J Oncol. 2016 Nov; 49(5): 1881-1889. doi: 10.3892/ijo.2016.3691 (SCI).

  29. Ming-Jenn Chen, Yi-Ling Chen, Tzu-Wen Wang, Hui-Ping Hsu, Ming-Derg Lai. The membrane bile acid receptor TGR5 predicts good prognosis in ampullary adenocarcinoma patients with hyperbilirubinemia. Oncology Reports. 2016 Oct; 36(4): 1997-2008 (SCI)

  30. Chih-Ming Su, Ting-Yu Chang, Hui-Ping Hsu, Hui-Huang Lai, Jie-Ning Li, Yu-Jhen Lyu, Kuang-Tai Kuo, Ming-Te Huang, Jen-Liang Su, Pai-Sheng Chen. A novel application of E1A in combination therapy with EGFR- TKI treatment in breast cancer. Oncotarget. 2016 Sep 27; 7(39): 63924-63936. doi: 10.18632/oncotarget.11737 (SCI)

  31. Chien-Yu Cho, Kuo-Ting Lee, Wei-Ching Chen, Chih-Yang Wang, Yung-Sheng Chang, Hau-Lun Huang, Hui-Ping Hsu, Meng-Chi Yen, Ming-Zong Lai, Ming-Derg Lai. MST3 promotes proliferation and tumorigenicity through the VAV2/Rac1 signal axis in breast cancer. Oncotarget. 2016 Feb 20; 7(6). doi: 10.18632/oncotarget.7542.e1-e19 (SCI)

  32. Hau-Lun Huang, Wei-Ching Chen, Hui-Ping Hsu, Chien-Yu Cho, Yu-Hsuan Hung, Chih-Yang Wang, Ming-Derg Lai. Argininosuccinate lyase is a potential therapeutic target in breast cancer. Oncology Reports. 2015 Dec; 34(6): 3131-3139 (SCI)

  33. Yan-Shen Shan, Yi-Ling Chen, Ming-Derg Lai, Hui-Ping Hsu. Nestin predicts a favorable prognosis in early ampullary adenocarcinoma and functions as a promoter of metastasis in advanced cancer. Oncology Reports. 2015 Dec; 33(1): 40-48 (SCI)

  34. Wei-Ching Chen, Yung-Sheng Chang, Hui-Ping Hsu, Meng-Chi Yen, Hau-Lun Huang, Chien-Yu Cho, Chih-Yang Wang, Tzu-Yang Weng, Po-Ting Lai, Ching-Shih Chen, Yih-Jyh Lin, Ming-Derg Lai. Therapeutics targeting CD90-integrin-AMPK-CD133 signal axis in liver cancer. Oncotarget. 2015 Dec 15; 6(40): 42923-42937 (SCI)

  35. Cheng-Lin Wu, Ying-Jui Chao, Ta-Ming Yang, Yi-Ling Chen, Kung-Chao Chang, Hui-Ping Hsu, Yan-Shen Shan, Ming-Derg Lai. Dual role of CD44 isoforms in ampullary adenocarcinoma: CD44s predicts poor prognosis in early cancer and CD44v is an indicator for recurrence in advanced cancer. BMC Cancer. 2015 Nov 16; 15(1): 903.e1-903.e10 (SCI)

  36. Ting-Wei Lin, Hui-Ping Hsu. Increased activity of factor VIII causing acute intestinal ischemic disorder with recurrent and multiple arterial thromboses. Formosan J Surg. 2015 Oct; 48(5): 177-180 (國內期刊：外科醫學會雜誌)

  37. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Wei-Ching Chen, Jung-Hua Fang, Tzu-Yang Weng, Yi-Ling Chen. Argininosuccinate synthetase 1 suppression and arginine restriction inhibit cell migration in gastric cancer cell lines. Scientific Reports. 2015 Apr 30; 5: 9783.e1-9783.e10. (SCI) 本人為共同第一作者

  38. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Yi-Pey Luo, Yi-Ling Chen. Increased expression of argininosuccinate synthetase protein predicts poor prognosis in human gastric cancer. Oncology Reports. 2015 Jan; 33(1): 49-57 (SCI) 本人為共同第一作者

  39. Yan-Shen Shan, Hui-Ping Hsu, Ming-Derg Lai, Meng-Chi Yen, Jung-Hua Fang, Tzu-Yang Weng, Yi-Ling Chen. Suppression of mucin 2 promotes interleukin-6 secretion and tumor growth in an orthotopic immune-competent colon cancer animal model. Oncology Reports. 2014 Dec; 32(6): 2335-2342 (SCI) 本人為共同第一作者

  40. Ying-Jui Chao, Edgar D Sy, Hui-Ping Hsu, Yan-Shen Shan. Predictors for resectability and survival in locally advanced pancreatic cancer after gemcitabine based neoadjuvant therapy. BMC Surgery. 2014 Sep 25; 14(9): 72.e1-72.e8 (SCI)

  41. Yu-Hsuan Hung, Yi-Shin Chan, Yung-Sheng Chang, Kuo-Ting Lee, Hui-Ping Hsu, Meng-Chi Yen, Wei-Ching Chen, Chih-Yang Wang, Ming-Derg Lai. Fatty acid metabolic enzyme acyl-CoA thioesterase 8 promotes the development of hepatocellular carcinoma. Oncology Reports. 2014 Jun; 31(6): 2797-2803 (SCI)

  42. Hau-Lun Huang, Hui-Ping Hsu, Shu-Chu Shieh, Yung-Sheng Chang, Wei-Ching Chen, Chien-You Cho, Chiao-Fang Teng, Ih-Jen Su, Wen-Chun Hung, Ming-Derg Lai. Attenuation of argininosuccinate lyase inhibits cancer growth via cyclin A2 and nitric oxide. Mol Cancer Ther. 2013 Nov; 12(11): 2505-2516 (SCI)

  43. Yao-Lung Kuo, Wen-Chung Chen, Wei-Jen Yao, Lili Cheng, Hui-Ping Hsu, Hung-Wen Lai, Shou-Jen Kuo, Dar-Ren Chen, Tsai-Wang Chang. Validation of Memorial Sloan-Kettering Cancer Center nomogram for prediction of non-sentinel lymph node metastasis in sentinel lymph node positive breast cancer patients an international comparison. Int J Surg. 2013 Aug; 11(7): 538-543 (SCI)

  44. Yan-Shen Shan, Jung-Hua Fang, Ming-Derg Lai, Meng-Chi Yen, Pin-Wen Lin, Hui-Ping Hsu, Chian-Yuh Lin, Yi-Ling Chen. Establishment of an orthotopic transplantable gastric cancer animal model for studying the immunological effects of new cancer therapeutic modules. Mol Carcinog. 2011 Oct; 50(10): 739-750 (SCI)

  45. I-Wen Lee, Lin Kang, Hui-Ping Hsu, Pao-Lin Kyo, Chia-Ming Chang. Puerperal mastitis requiring hospitalization during a nine-year period. Am J Obstet Gynecol. 2010 Oct; 203(4): 332.e1-e6 (SCI)

  46. Te-Ling Lu, Guan-Jhong Huang, Huang-Joe Wang, Jian-Lian Chen, Hui-Ping Hsu, Te-Jung Lu. Hispolon promotes MDM2 downregulation through chaperone-mediated autophagy. Biochem Biophys Res Commun. 2010 Jul; 398(1): 26-31 (SCI)

  47. Hui-Ping Hsu, Yan-Shen Shan, Ming-Derg Lai, Pin-Wen Lin. Osteopontin-positive infiltrating tumor-associated macrophages in bulky ampullary cancer predict survival. Cancer Biol Ther. 2010 Jul 15; 10(2): 144-154 (SCI)

  48. Hui-Ping Hsu, Yan-Shen Shan, Pin-Wen Lin, Ying-Tai Jin, Ming-Derg Lai. Loss of E-cadherin and β-catenin is correlated with poor prognosis of ampullary neoplasms. J Surg Oncol. 2010 Apr 1; 101(5): 356-362 (SCI)

  49. Hui-Ping Hsu. Prognosis of ampullary carcinoma after radical resection and its carcinogenesis. Formos J Surg. 2008 Dec; 41(6): 257-261 (國內期刊：外科醫學會雜誌) (Mini Review)

  50. Hui-Ping Hsu, Yan-Shen Shan, Yu-Hsiang Hsieh, Ta-Ming Yang, Pin-Wen Lin. Predictors of recurrence after pancreaticoduodenectomy in ampullary cancer: comparison between non-， early and late recurrence. J Formos Med Assoc. 2007 Jun; 106(6): 432-443 (SCI)

  51. Paul J. Karanicolas, Edward Davies, Regina Kunz, Matthias Briel, H. Pavan Koka, Darrin M. Payne, Shona E. Smith, Hui-Ping Hsu, Pin-Wen Lin, Christian Bloechle, Karl-Joseph Paquet and Gordon H. Guyatt. The pylorus: take it or leave it? Systemic review and meta-analysis of pylorus-preserving versus standard Whipple pancreaticoduodenectomy for pancreatic or periampullary cancer. Ann Surg Oncol. 2007 Jun; 14(6): 1825-1834 (SCI)

  52. Hui-Ping Hsu, Ta-Ming Yang, Yu-Hsiang Hsieh, Yan-Shen Shan, Pin-Wen Lin. Predictors for patterns of failure after pancreaticoduodenectomy in ampullary cancer. Ann Surg Oncol. 2007 Jan; 14(1): 50-60 (SCI)

  53. Hui-Ping Hsu, Yan-Shen Shan, Yu-Hsiang Hsieh, Edgar D. Sy, Pin-Wen Lin. Impact of Etiologic factors and APACHE II and POSSUM scores in management and clinical outcome of acute intestinal ischemic disorders after surgical treatment. World J Surg. 2006 Dec; 30(12): 2152-2162 (SCI)

  54. Hui-Ping Hsu, Yan-Shen Shan, Edgar D. Sy, Pin-Wen Lin. Acute mesentery venous occlusion in patients with warfarin – warfarin therapy may complicate the diagnosis of intestinal vascular complication. Formosan J Surgery. 2005 Feb; 38(1): 13-19 (國內期刊：外科醫學會雜誌)

  55. Yan-Shen Shan, Hui-Ping Hsu, Yu-Hsiang Hsieh, Edgar D. Sy, Jenq-Chang Lee, Pin-Wen Lin. The significance of intraoperative peritoneal fungus culture in perforated peptic ulcer. Br J Surg. 2003 Oct; 90: 1215-9 (SCI)

  56. Hui-Ping Hsu, Pao-Lin Kuo, Meng-Hsing Wu, Ta-Jen Wu, Yuan-Chang Dai, Ching-Cherng Tzeng, Shio-Jean Lin. Microscopic gonadoblastoma in a patient with 46，XY gonadal dysgenesis. Taiwanese J Obstet Gynecol 2001; 40: 77-81. (SCI)

  57. Nina Tsao, Hui-Ping Hsu, Ching-Ming Wu, Ching-Chuan Liu, Huan-Yao Lei. TNF causes an increase in blood-brain barrier permeability during sepsis. J Med Microbiol. 2001 Sep; 50(9): 812-821 (SCI).

  58. Nina Tsao, Hui-Ping Hsu, Huan-Yao Lei. TNFalpha-induced cyclooxygenase-2 not only increases the vasopermeability of blood-brain barrier but also enhances the neutrophil survival in Escherichia coli-induced brain inflammation. Prostaglandins & Other Lipid Mediators. 1999 Jul; 57(5-6): 371-382 (SCI)