國立成功大學醫學院生化所

助理教授

余建泓 博士

Dr. Chien-hung Yu

English Main Page

研究專長

研究興趣及方向


Selected Publications:

  1. Zhou, Z., Dang, Y., Zhou, M., Li, L., Yu, C.H., Fu, J., Chen, S., and Liu, Y. (2016) Codon usage is an important determinant of gene expression levels largely through its effects on transcription. Proc. Natl. Acad. Sci. U.S.A., 113, E6117-E6125. [Abstract]

  2. Yu, C.H.*, Dang, Y.*, Zhou, Z*., Wu, C., Zhao, F., Sachs, M.S., and Liu, Y. (2015) Codon usage influences the local rate of translation elongation to regulate co-translational protein folding. Mol. Cell, 59, 744-754. (*co-first authors) (Cover article and highlighted in TIBS) [Abstract]

  3. Yu, C.H. and Olsthoorn, R.C. (2015) Monitoring ribosomal frameshifting as a platform to screen anti-riboswitch drug candidates. Methods Enzymol.,550, 385-393. [Abstract]

  4. Yu, C.H. and Olsthoorn, R.C. (2014) Stimulation of ribosomal frameshifting by RNA G-quadruplex structures. Nucleic Acids Res., 42, 1887-1892. [Abstract]

  5. Luo, J., Wärmländer, S.K., Yu, C.H., Muhammad, K., Gräslund, A., and Abrahams, J.P. (2014) The Aβ peptide forms non-amyloid fibrils in the presence of carbon nanotubes. Nanoscale., 6(12):6720-6. [Abstract]

  6. Luo, J., Otero, J.M., Yu, C.H., Wärmländer, S.K., Gräslund, A., Overhand, M., and Abrahams, J.P. (2013) Inhibiting and reversing amyloid-β peptide (1-40) fibril formation with gramicidin S and engineered analogues. Chemistry, 19, 17338-17348. [Abstract]

  7. Luo, J., Yu, C.H., Yu, H., Borstnar, R., Kamerlin, S.C., Gräslund, A., Abrahams, J.P., and Wärmländer, S.K. (2013) Cellular polyamines promote amyloid-beta (Aβ) peptide fibrillation and modulate the aggregation pathways. ACS Chem. Neurosci., 4, 454-62. [Abstract]

  8. Yu, C.H. Luo J., Iwata-Reuyl, D., and Olsthoorn, R.C. (2013) Exploiting preQ1 riboswitches to regulate ribosomal frameshifting. ACS Chem. Biol., 8, 733-740. [Abstract]

  9. Yu, C.H., Noteborn, M.H., Pleij, C.W., and Olsthoorn, R.C. (2011) Stem-loop structures can effectively substitute for an RNA pseudoknot in -1 ribosomal frameshifting. Nucleic Acids Res., 39, 8952-8959. [Abstract]

  10. Yu, C.H., Noteborn, M.H., and Olsthoorn, R.C. (2010) Stimulation of ribosomal frameshifting by antisense LNA. Nucleic Acids Res., 38, 8277-8283. [Abstract]

  11. Lien, H.Y., Yu, C.H., Liou, C.M., and Wu, W.F. (2009) Regulation of clpQY (hslVU) Gene Expression in Escherichia coli. Open Microbiol. J., 3, 29-39. [Abstract]

  12. Lee, Y.Y., Chang, C.F., Kuo, C.L., Chen, M.C., Yu, C.H., Lin, P.I., and Wu, W.F. (2003) Subunit oligomerization and substrate recognition of the Escherichia coli ClpYQ (HslUV) protease implicated by in vivo protein-protein interactions in the yeast two-hybrid system. J. Bacteriol., 185, 2393-2401. [Abstract]


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Updated: 2017.01.03